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The main purpose of this study was to determine whether the BUD extension with the use of a CSTD had a financial benefit from decreasing waste that would offset the cost of implementation of the CSTD at a comprehensive CCC.Secondary objectives included a count of the number of parenteral antineoplastic and biologic agents compounded in the CCC, measured employee exposure to HDs, determined cost savings from being able to use larger bulk vials of products, and a survey of the use of CSTDs in other Michigan hospitals.There were 32 vials per study group, for a total of 288 vials.The vials were incubated for 14 days, after which none that had been accessed using Equashield had microbial growth.All positive controls demonstrated growth within 48 hours of inoculation and all negative controls showed no growth for the duration of the study.
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A wipe study by Chemo GLO was done as directed by USP pre-implementation of a CSTD to assess for employee » exposure to HDs in the pharmacy, nursing, and patient areas. Of these 5 HDs, 4 were commonly compounded in the CCC.
One HD that was tested acted as a control because it was not dispensed in the CCC.
For the primary outcome, a Microsoft Excel spreadsheet was used to record the data and perform the calculations.
The calculation performed was: [(The price of the drug saved by using extended BUD the price of the CSTDs not used on the vials that were saved with extended BUD) – The price of the CSTDs that would have been used = The cost of implementing a CSTD].
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