Validating microarray data nitrogen dating method

Posted by / 24-Jan-2020 09:41

An exon junction array design uses probes specific to the expected or potential splice sites of predicted exons for a gene.

It is of intermediate density, or coverage, to a typical gene expression array (with 1–3 probes per gene) and a genomic tiling array (with hundreds or thousands of probes per gene).

Analogously to Ch IP, genomic regions bound by a protein of interest can be isolated and used to probe a microarray to determine binding site occupancy.This approach can be used to discover new drugs and biologicals that have the ability to inhibit gene expression.Microarrays can be manufactured in different ways, depending on the number of probes under examination, costs, customization requirements, and the type of scientific question being asked.Genome tiling arrays consist of overlapping probes designed to densely represent a genomic region of interest, sometimes as large as an entire human chromosome.The purpose is to empirically detect expression of transcripts or alternatively spliced forms which may not have been previously known or predicted.

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